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Virus research provides additional information but does not provide multiple sclerosis cause

Medical Update Memo
September 3, 1998

Summary
Research linking multiple sclerosis (MS) to a common virus provides additional useful information to uncovering what triggers the MS process but has not yet provided the cause for this often disabling disease of the central nervous system.

Background
Investigators at the University of Wisconsin reported earlier this week at a medical meeting in Montreal that they had found evidence of the human herpes virus-6 (HHV-6) in the blood and tissue of a small number of people with MS.

"This is one of several reports in the past few years suggesting a possible link between HHV- 6 and MS, and it adds to the general body of knowledge. However, this does not mean that HHV-6 is the cause of MS," emphasized Dr. William J. McIlroy, national medical advisor for the Multiple Sclerosis Society of Canada.

"It is possible that MS may be triggered by any one of a number of common viruses in people who are genetically susceptible to developing the disease. Other viruses under investigation in Canada, the United States and Europe are those that cause upper respiratory tract infections, chicken pox and measles," he explained.

Several small clinical trials are underway to determine if anti-viral therapies might be effective against HHV-6. At this point, there is no evidence that such therapies will be useful in the treatment of MS.

HHV-6 is a common virus to which most people have been exposed. It causes roseola, an illness characterized by short-term fever and a rash, in young children.

Multiple sclerosis is a disease of the central nervous system. Unpredictable attacks can lead to symptoms ranging from numbness to mobility problems to paralysis. Canada is a high risk area for the disease which affects an estimated 50,000 Canadians.

People wishing more information about the HHV-6 virus and other aspects of MS may contact the Multiple Sclerosis Society of Canada at 1 800 268-7582.

Disclaimer
The Multiple Sclerosis Society of Canada is an independent, voluntary health agency and does not approve, endorse or recommend any specific product or therapy but provides information to assist individuals in making their own decisions.

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