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Summary: Myelin is a fatty substance that protects nerve cells and acts to enhance their signal transmission. MS results from abnormal activity of the immune system whereby the body’s own immune cells target and damage myelin and myelin-producing cells called oligodendrocytes located in the central... Read the full article
Summary: Chronic pain has a major effect on the quality of life of people diagnosed with multiple sclerosis (MS). Chronic pain is reported to a much higher degree and rate in females with MS than men. Why females are impacted by chronic pain in MS more than men is still unknown. The research team will:... Read the full article
Summary: Inflammasomes are protein complexes in the immune system that are activated by infection. These complexes are also activated in multiple sclerosis (MS) and promote inflammation and brain injury. The factors regulating inflammasomes in progressive MS are unclear. The research team will: Identify... Read the full article
Summary: Magnetic Resonance Imaging (MRI) is heavily used in multiple sclerosis (MS). It is highly effective for diagnosis of the disease. MRI is far less effective at tracking the disease progression and its response to therapy, largely due to reliance on only lesion measures. Other quantitative measures... Read the full article
Background: It is estimated that half of all individuals with multiple sclerosis (MS) experience chronic pain. Chronic ‘neuropathic’ pain is particularly distressing, because conventional analgesic therapies are largely ineffective or are associated with dose-limiting side effects. The development of... Read the full article
