Multiple Sclerosis Society of Canada

Research We Fund

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Improving cognition in people with Progressive Multiple Sclerosis: A Multi-Arm, Randomized, Blinded, Sham-Controlled Trial of Cognitive Rehabilitation and Aerobic Exercise

Project Summary: Cognition is considered an “invisible” symptom that can affect up to 70% of people with progressive MS and has been identified as an area of prime concern by people with MS given the harmful effects on employment, relationships and activities of daily living. There is an essential need... Read the full article

MRI of Deep Grey Matter in multiple sclerosis

Summary: Magnetic Resonance Imaging (MRI) is heavily used in multiple sclerosis (MS). It is highly effective for diagnosis of the disease. MRI is far less effective at tracking the disease progression and its response to therapy, largely due to reliance on only lesion measures. Other quantitative measures... Read the full article

Web-based physiotherapy in moderate to severe MS

Project Description: Persons with MS may find it challenging to participate in regular physical activity or exercise, which is activity done to improve health and/or fitness. This is due to a number of reasons: exercise programs tailored to individuals with significant mobility impairments may be difficult... Read the full article

Progressive degeneration from onset in pediatric multiple sclerosis: Evaluation of clinical and health-related quality of life, early loss of brain integrity and accelerated immunological senescence

Investigators: Dr. Brenda Banwell , Children’s Hospital of Philadelphia Dr. Ruth Ann Marrie , Health Science Centre Winnipeg Dr. Amit Bar-Or , McGill University Dr. Douglas Arnold , McGill University Dr. Ann Yeh , Hospital for Sick Children Project Summary: Most people think of multiple sclerosis (MS)... Read the full article

Cancer in Multiple Sclerosis: Diagnosis and Outcomes

Summary: People with MS often have co-existing health conditions such as cancer. Cancer is the most common cause of death in people with MS after MS itself. Cancers of the breast, colon and rectum are among the most common cancers that affect Canadians, however we do not know very much about how often... Read the full article

Predicting Disease Deterioration in Multiple Sclerosis

Background: A current limitation in multiple sclerosis (MS) care is the ability to accurately predict whether a person’s MS will worsen and when, since the disease trajectory differs for each individual with MS. Being able to better predict a person’s disease trajectory can influence the healthcare... Read the full article

Subclinical Atherosclerosis in Multiple Sclerosis

Background: Atherosclerosis is condition in which the arteries are narrowed due to a build-up of plaque. The plaque is made up of fat, cholesterol, clotting material from the blood and other factors. Atherosclerosis can occur silently without any clinical symptoms, this is called subclinical atherosclerosis... Read the full article

Characteristics of NMOSD and MOGAD in Canada

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) are inflammatory diseases of the central nervous system that mimic MS and are often highly disabling. These conditions do not respond to most multiple sclerosis (MS)... Read the full article

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