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Summary: Epstein-Barr Virus (EBV) is the most common cause of infectious mononucleosis, an illness highly prevalent among adolescents. Adolescents and young adults with clinically diagnosed infectious mononucleosis have a high risk of developing multiple sclerosis (MS). The factors linking mononucleosis... Read the full article
Summary: Early evidence is looking at human immunodeficiency virus (HIV) association with lowering risk of developing multiple sclerosis (MS). Whether HIV is truly associated with lower risk by its ability to weaken the immune system or through drug therapies for HIV is unknown. The research team will:... Read the full article
Affiliation: Institut national de la recherche scientifique (INRS) Summary: Bacillus Calmette-Guerin (BCG) vaccine, which is normally given to protect against tuberculosis, can slow short-term multiple sclerosis (MS) progression. It is unknown if having received the BCG vaccine as a child could prevent... Read the full article
Co-Principal Investigators: Dr. Gary Van Domelaar, Dr. Charles Bernstein, Dr. Morag Graham Summary: The gut microbiome is home to trillions of microorganisms including bacteria, fungi, parasites, and viruses. The primary focus for researchers when studying the gut microbiome in multiple sclerosis (MS)... Read the full article
Summary: Western diet, obesity and related comordities are risk factors for MS onset and progression. Scientific evidence shows that restricting intake of methionine, an essential amino acid found in high-levels in meat-based diets, is associated with a prolonged lifespan (anti-aging), slower cancer... Read the full article
Summary: The goal of the research is to better understand the role of Epstein-Barr Virus (EBV) in the development and progression of MS. EBV is a common virus that infects people in childhood or early adulthood and remains quiet (causes a latent EBV infection) in our immune system. Project Description:... Read the full article
Summary: Research suggests that Epstein- Barr virus (EBV), the causative agent of mononucleosis, is a potential trigger of multiple sclerosis (MS). The mechanisms regulating MS in individuals infected by EBV is unknown. The research team will: Investigate the immune response in animals with MS-like... Read the full article
Background: Recognizing and diagnosing multiple sclerosis (MS) in children and youth can be challenging. There is a need for better evidence that helps doctors and researchers recognize when MS actually starts, recognizing the earliest warning signs of the disease, in order to provide prompt treatment... Read the full article
Investigators: Dr. Helen Tremlett , The University of British Columbia Dr. Emmanuelle Waubant , University of California San Francisco Dr. Charles Bernstein , University of Manitoba Dr. Gary Van Domselaar , University of Manitoba Dr. Morag Graham , University of Manitoba Project Summary: Microbial communities... Read the full article
