Multiple Sclerosis Society of Canada

Research We Fund

Filter Current filters include: Ontario

The Role of Antibody-Secreting Cells in MS/EAE

Summary: B cells have a dual role in multiple sclerosis (MS). A subset of B cells slow the disease course in MS while another subset have detrimental effects on MS. The gut microbiome is the richest source of B cells. The role of a subset of B cells, called plasma cells, found in the gut microbiome... Read the full article

Characteristics of NMOSD and MOGAD in Canada

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) are inflammatory diseases of the central nervous system that mimic MS and are often highly disabling. These conditions do not respond to most multiple sclerosis (MS)... Read the full article

Immigration and the risk of multiple sclerosis

Summary: Canada is known to have one of the highest multiple sclerosis (MS) rates in the world and while the risk of developing MS is lower in immigrants, it is still higher than in their native countries. It remains unknown why the Canadian environment may pose higher risk to develop MS. The research... Read the full article

Biomarkers in MS during pregnancy and postpartum

Summary: MS relapses are less common during pregnancy, but up to 30% of women have a relapse in the three months after delivery. Since MRI is not routinely performed during pregnancy, measuring the levels of emerging blood biomarkers (neurofilament light chain (or sNfL); glial fibrillary acidic protein... Read the full article

The Ageing Microbiome and Progressive MS

Summary: The composition of the gut microbiome, the community of microbes that reside in the gut, can influence immune function and neuroinflammation in brain diseases such as MS. By introducing gut microbiota from specific sub-groups of MS patients in an animal model of secondary progressive MS (SPMS)... Read the full article

Progressive degeneration from onset in pediatric multiple sclerosis: Evaluation of clinical and health-related quality of life, early loss of brain integrity and accelerated immunological senescence

Investigators: Dr. Brenda Banwell , Children’s Hospital of Philadelphia Dr. Ruth Ann Marrie , Health Science Centre Winnipeg Dr. Amit Bar-Or , McGill University Dr. Douglas Arnold , McGill University Dr. Ann Yeh , Hospital for Sick Children Project Summary: Most people think of multiple sclerosis (MS)... Read the full article

Improving cognition in people with Progressive Multiple Sclerosis: A Multi-Arm, Randomized, Blinded, Sham-Controlled Trial of Cognitive Rehabilitation and Aerobic Exercise

Project Summary: Cognition is considered an “invisible” symptom that can affect up to 70% of people with progressive MS and has been identified as an area of prime concern by people with MS given the harmful effects on employment, relationships and activities of daily living. There is an essential need... Read the full article

Open navigation