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Human immunodeficiency virus, antiretroviral drugs and multiple sclerosis risk (HIV-MS)

Summary: Early evidence is looking at human immunodeficiency virus (HIV) association with lowering risk of developing multiple sclerosis (MS). Whether HIV is truly associated with lower risk by its ability to weaken the immune system or through drug therapies for HIV is unknown. The research team will:... Read the full article

Assessing safety monitoring in patients taking oral multiple sclerosis treatments [ASYMPTOTE]

Summary: Disease-modifying therapies (DMTs) that were given by injection first became available for people with multiple sclerosis (MS). More recently, DMTs that are given by mouth have entered the market. Although these oral drugs provide more choice for people with MS, concerns over their safety have... Read the full article

From bugs to brains: the gut microbiome in paediatric multiple sclerosis

Investigators: Dr. Helen Tremlett , The University of British Columbia Dr. Emmanuelle Waubant , University of California San Francisco Dr. Charles Bernstein , University of Manitoba Dr. Gary Van Domselaar , University of Manitoba Dr. Morag Graham , University of Manitoba Project Summary: Microbial communities... Read the full article

It’s a fungal world: the mycobiome in pediatric MS

Co-Principal Investigators: Dr. Gary Van Domelaar, Dr. Charles Bernstein, Dr. Morag Graham Summary: The gut microbiome is home to trillions of microorganisms including bacteria, fungi, parasites, and viruses. The primary focus for researchers when studying the gut microbiome in multiple sclerosis (MS)... Read the full article

Pediatric Multiple Sclerosis: Prevalence to Prodrome (ProMS-Peds)

Background: Recognizing and diagnosing multiple sclerosis (MS) in children and youth can be challenging. There is a need for better evidence that helps doctors and researchers recognize when MS actually starts, recognizing the earliest warning signs of the disease, in order to provide prompt treatment... Read the full article