Research We Fund
Summary: One type of immune cell, call the B cell, can have either anti- or pro-inflammatory properties. The function of the B cell is also thought to be influenced by microbes in the gut microbiome. B cells function is believed to be compromised in multiple sclerosis (MS) and how the gut microbiome...
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Summary: B cells have a dual role in multiple sclerosis (MS). A subset of B cells slow the disease course in MS while another subset have detrimental effects on MS. The gut microbiome is the richest source of B cells. The role of a subset of B cells, called plasma cells, found in the gut microbiome...
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Summary: This study is examining the molecular and cellular factors that drive multiple sclerosis (MS) progression. Using a novel animal model and human samples, this research aims to understand the effect of both age and microbes in the gut on MS progression. Project Description: The molecular basis...
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Lead Investigators: Dr. Jennifer Gommerman (University of Toronto) Dr. Alexandre Prat (University of Montreal) Project Description: This project aims to shed light on how most people with relapsing-remitting multiple sclerosis (MS) (RRMS) transition to a secondary progressive phase of MS (SPMS) and...
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